NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss

Mapping and quantifying mammalian transcriptomes by RNA-Seq

A Mortazavi, Brian A. Williams, Kenneth McCue et al. · Nature Methods · 2008 · 14K citations

Functional Genomics, Genetics, Transcriptomics Technology +7

A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Hadas Keren‐Shaul, Amit Spinrad, Assaf Weiner et al. · Cell · 2017 · 5.2K citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +10

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

Timothy R. Hammond, Connor Dufort, Lasse Dissing‐Olesen et al. · Immunity · 2018 · 2.2K citations · Full text

Inflammation, Neurodegenerative Diseases, Mouse Lifespan +12

Motor skill learning requires active central myelination

Ian A. McKenzie, David Ohayon, Huiliang Li et al. · Science · 2014 · 1.1K citations · Full text

Motor Learning, Motor Skill, Developmental Cognitive Neuroscience +17

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

Yuchen Chien, Claudio Scuoppo, Xiaowo Wang et al. · Genes & Development · 2011 · 956 citations · Full text

Aging, Immunology, Immune Regulation +19