The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgery · 2023 · 26 citations · 62 references
MedicineNeurosurgeryOncologyNeuro-oncologyTreatment PlanningTumor PathologyBrain TumorsCentral Nervous System TumorsMeningioma RadiotherapyNeurologic ImagingPostoperative Radiotherapy For Brain TumorsTumor GradingBenign Intracranial TumorsBrain Tumor DiagnosisBrain Tumor PathologyHistopathology Of Brain TumorsIntraoperative Radiation TherapyMeningioma PathologyResection Of MeningiomaWorld Health Organization Histologic Classification
Meningiomas are the most common intracranial tumors in adult patients. Although the majority of meningiomas are diagnosed as benign, approximately 20% of cases are high-grade tumors that require significant clinical treatment. The gold standard for grading central nervous system tumors comes from the World Health Organization Classification of Tumors of the central nervous system. Treatment options also depend on the location, imaging, and histopathological features of the tumor. This review will cover diagnostic strategies for meningiomas, including 2021 updates to the World Health Organization's grading of meningiomas. Meningioma treatment plans are variable and highly dependent on tumor grading. This review will also update the reader on developments in the treatment of meningiomas, including surgery, radiation therapy and monoclonal antibody treatment.
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Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
Priscilla K. Brastianos, Peleg Horowitz, Sandro Santagata et al. · Nature Genetics · 2013 · 652 citations · Full text
TERT Promoter Mutations and Risk of Recurrence in Meningioma
Felix Sahm, Daniel Schrimpf, Adriana Olar et al. · JNCI Journal of the National Cancer Institute · 2015 · 400 citations · Full text