A tumor-specific ROS self-supply enhanced cascade-responsive prodrug activation nanosystem for amplified chemotherapy against multidrug-resistant tumors

Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells

Feng Wang, Yucai Wang, Shuang Dou et al. · ACS Nano · 2011 · 803 citations

Nanoparticles, Nanomedicine, Acidic Organelles +15

A Tumor‐Specific Cascade Amplification Drug Release Nanoparticle for Overcoming Multidrug Resistance in Cancers

Mingzhou Ye, Yuxin Han, Jianbin Tang et al. · Advanced Materials · 2017 · 335 citations

Nanoparticles, Nanotherapeutics, Tumor Biology +17

Doxorubicin and Paclitaxel-Loaded Lipid-Based Nanoparticles Overcome Multidrug Resistance by Inhibiting P-Glycoprotein and Depleting ATP

Xiaowei Dong, Cynthia A. Mattingly, Michael T. Tseng et al. · Cancer Research · 2009 · 283 citations · Full text

Nanomedicine, Paclitaxel Nanoparticles, Health Sciences +15

Large Pore‐Sized Hollow Mesoporous Organosilica for Redox‐Responsive Gene Delivery and Synergistic Cancer Chemotherapy

Meiying Wu, Qingshuo Meng, Yu Chen et al. · Advanced Materials · 2016 · 271 citations

pH‐ and NIR Light‐Responsive Micelles with Hyperthermia‐Triggered Tumor Penetration and Cytoplasm Drug Release to Reverse Doxorubicin Resistance in Breast Cancer

Haijun Yu, Zhirui Cui, Pengcheng Yu et al. · Advanced Functional Materials · 2015 · 249 citations

Nanotherapeutics, Engineering, Responsive Polymers +20