Concepedia

Publication | Open Access

TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer

DOIFull Paper Access

15

Citations

44

References

2023

Year

Aditi S. Khatpe, Rebecca Dirks, Poornima Bhat‐Nakshatri, Henry Mang, Katie Batic, Sarah Swiezy, Jacob Duane Olson, Xi Rao, Yue Wang, Hiromi Tanaka,
Cancer Research

Abstract

The chr.8q24.3 amplicon-resident gene TONSL is upregulated during the initial steps of tumorigenesis to support neoplastic transformation by increasing DNA repair and represents a potential therapeutic target for treating breast cancer.

References

YearCitations

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