L‐carnitine alleviates cardiac microvascular dysfunction in diabetic cardiomyopathy by enhancing <scp>PINK1‐Parkin</scp>‐dependent mitophagy through the <scp>CPT1a‐PHB2‐PARL</scp> pathways

Abstract

L-carnitine treatment enhanced PINK1-Parkin-dependent mitophagy by maintaining the PHB2-PARL interaction via CPT1a, thereby reversing mitochondrial dysfunction and cardiac microvascular injury in diabetic cardiomyopathy.