¹⁸F-AV45 PET and MRI Reveal the Influencing Factors of Alzheimer’s Disease Biomarkers in Subjective Cognitive Decline Population

Abstract

In SCD, APOE ɛ4 gene, age, and sex significantly influenced Aβ deposition and APOE ɛ4 gene can interact with age in impacting Aβ deposition. Both age and sex can affect GM atrophy. The results suggested that female SCD with APOE ɛ4 genes and aged more than 60 years old might exhibit advanced AD biomarkers.