Concepedia

Publication | Open Access

EZH2 inhibition dampens autoantibody production in lupus by restoring B cell immune tolerance

DOIFull Paper Access

11

Citations

34

References

2023

Year

Yiying Yang, Muyuan Li, Yaxi Zhu, Ke Liu, Meidong Liu, Yanjuan Liu, Ganqian Zhu, Hui Luo, Xiaoxia Zuo, Huali Zhang,
International Immunopharmacology

Abstract

EZH2 mediated the breakdown of B-cell peripheral immune tolerance by inhibiting CKI genes and participated in the generation of autoantibodies in SLE. EZH2 inhibition could serve as a promising drug intervention for the treatment of SLE.

References

YearCitations

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