Development of Novel Topical Anti-Acne Cream Containing Postbiotics for Mild-to-Moderate Acne

Abstract

The anti-acne skincare cream was found to be safe and not cause any irritation. Significant improvements in the acne lesion proportion (<i>P</i> < 0.01), transepidermal water loss (<i>P</i> < 0.001), and sebum secretion (<i>P</i> < 0.05) were observed in comparison to the baseline in the subjects. The analysis of the statistical data after 4 weeks of treatment showed a positive decrease in skin tone, stratum corneum hydration, and superficial pH without statistical significance, compared with the baseline. The results of this study suggest that the topical application of the anti-acne skincare cream was effective and safe in subjects with mild-to-moderate acne and could represent an optional complement for acne treatments.