Concepedia

Publication | Open Access

Extrachromosomal Amplification of Human Papillomavirus Episomes Is a Mechanism of Cervical Carcinogenesis

DOIFull Paper Access

27

Citations

51

References

2023

Year

Nicole M. Rossi, Jieqiong Dai, Yi Xie, Darawalee Wangsa, Kerstin Heselmeyer‐Haddad, Hong Lou, Joseph F. Boland, Meredith Yeager, Roberto Orozco, Enrique Alvirez Freites,
Cancer Research

Abstract

Multimers of the HPV genome are generated in cervical tumors replicating as extrachromosomal episomes, which is associated with deletion and rearrangement of the HPV genome and provides a mechanism for oncogenesis without integration.

References

YearCitations

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