Vitamin D improves hepatic steatosis in NAFLD via regulation of fatty acid uptake and β-oxidation - Concepedia

Concepedia

Publication | Open Access

Vitamin D improves hepatic steatosis in NAFLD via regulation of fatty acid uptake and β-oxidation

DOI Full Paper Access

39

Citations

49

References

2023

Year

Tingwan Du, Xiang Lian, Jingjing Zhang, Chunmei Yang, Wenxin Zhao, Jialu Li, Yong Zhou, Ling Ma

Frontiers in Endocrinology

Abstract

The study revealed that an adequate VD level may act as a protective factor in NAFLD and that VD may alleviate hepatic steatosis <i>via</i> the PPARα signaling pathway.

References

	Year	Citations
[Guidelines of prevention and treatment for nonalcoholic fatty liver disease: a 2018 update]. PubMed ObesityMetabolic Associated SteatohepatitisHepatic DisordersHepatologyMetabolic Associated Steatotic Liver Disease	2018	168
Inhibition of peroxisome-proliferator-activated receptor (PPAR)α by MK886 James P. Kehrer, Shyam Biswal, Eunhye La, Biochemical Journal	2001	150
Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity Yan Fang, Qi Wang, Ming Lu, Journal of Hepatology Metabolic SyndromeSrebp-1c ActivityHepatologyBiochemistryLiver Physiology	2014	142
Fenofibrate, a PPARα agonist, reduces hepatic fat accumulation through the upregulation of TFEB-mediated lipophagy Jin Yoo, In‐Kyung Jeong, Kyu Jeung Ahn, Metabolism Metabolic SyndromeMolecular PharmacologyHepatic Fat AccumulationBiochemistryLipid Nutrition	2021	100
Specific Strains of Faecalibacterium prausnitzii Ameliorate Nonalcoholic Fatty Liver Disease in Mice in Association with Gut Microbiota Regulation Wenbing Hu, Wenyu Gao, Zongmin Liu, Nutrients	2022	93
Berberine alleviates lipid metabolism disorders via inhibition of mitochondrial complex I in gut and liver Muyu Yu, Miriayi Alimujiang, Lili Hu, International Journal of Biological Sciences Lipid PeroxidationOxidative StressMetabolic SyndromeMetabolic SignalingHealth Sciences	2021	91
1,25(OH)<sub>2</sub>D<sub>3</sub> attenuates hepatic steatosis by inducing autophagy in mice Renlong Li, Enshuang Guo, Jiankun Yang, Obesity	2017	86
Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis Chanbin Lee, Ji‐Eun Kim, Jinsol Han, Nature Communications	2022	77
Low vitamin D levels and non-alcoholic fatty liver disease, evidence for their independent association in men in East China: a cross-sectional study (Survey on Prevalence in East China for Metabolic Diseases and Risk Factors (SPECT-China)) Hualing Zhai, Ningjian Wang, Bing Han, British Journal Of Nutrition	2016	76
Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells Qingqing Yu, Yayun Liu, Yufei Wu, Biomedicine & Pharmacotherapy Insulin ResistanceMetabolic SyndromeOxysterolBiochemistryLipid Accumulation	2018	63

Page 1