Concepedia

Vitamin D improves hepatic steatosis in NAFLD via regulation of fatty acid uptake and β-oxidation

Tingwan Du, Xiang Lian, Jingjing Zhang, Chunmei Yang, Wenxin Zhao, Jialu Li, Yong Zhou, Ling Ma

Frontiers in Endocrinology · 2023 · 39 citations · 49 references

Open access

Abstract

The study revealed that an adequate VD level may act as a protective factor in NAFLD and that VD may alleviate hepatic steatosis <i>via</i> the PPARα signaling pathway.

References

49

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PubMed · 2018 · 168 citations

Obesity, Metabolic Associated Steatohepatitis, Hepatic Disorders +10

Inhibition of peroxisome-proliferator-activated receptor (PPAR)α by MK886

James P. Kehrer, Shyam Biswal, Eunhye La et al. · Biochemical Journal · 2001 · 150 citations · Full text

Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity

Yan Fang, Qi Wang, Ming Lu et al. · Journal of Hepatology · 2014 · 142 citations

Metabolic Syndrome, Srebp-1c Activity, Hepatology +11

Fenofibrate, a PPARα agonist, reduces hepatic fat accumulation through the upregulation of TFEB-mediated lipophagy

Jin Yoo, In‐Kyung Jeong, Kyu Jeung Ahn et al. · Metabolism · 2021 · 100 citations

Metabolic Syndrome, Molecular Pharmacology, Hepatic Fat Accumulation +13

Specific Strains of Faecalibacterium prausnitzii Ameliorate Nonalcoholic Fatty Liver Disease in Mice in Association with Gut Microbiota Regulation

Wenbing Hu, Wenyu Gao, Zongmin Liu et al. · Nutrients · 2022 · 93 citations · Full text