Concepedia

Enhanced cell growth, production, and mAb quality produced in Chinese hamster ovary-K1 cells by supplementing polyamine in the media

Da Eun Kang, Yeong Bin An, Yeunju Kim, Seawon Ahn, Young Jin Kim, Jung Soo Lim, Soo Ryu, Hyoju Choi, Jiseon Yoo, Weon‐Kyoo You,

Applied Microbiology and Biotechnology · 2023 · 14 citations · 30 references

DOI

Concepts

References

30

Activation of <i>SAT1</i> engages polyamine metabolism with p53-mediated ferroptotic responses

Yang Ou, Shang-Jui Wang, Dawei Li et al. · Proceedings of the National Academy of Sciences · 2016 · 748 citations · Full text

, , +14

Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells

Swati Mandal, Ajeet Mandal, Hans E. Johansson et al. · Proceedings of the National Academy of Sciences · 2013 · 288 citations · Full text

, , +11

Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure

Sang Jick Kim, No Soo Kim, Chun Jeih Ryu et al. · Biotechnology and Bioengineering · 1998 · 221 citations

, , +17

Modeling Hybridoma Cell Metabolism Using a Generic Genome-Scale Metabolic Model of Mus musculus

Kashif Sheikh, Jochen Förster, Lars K. Nielsen · Biotechnology Progress · 2005 · 191 citations

, , +17

Polyamine starvation causes disappearance of actin filaments and microtubules in polyamine-auxotrophic CHO cells

Pirkko Pohjanpelto, Ismo Virtanen, Erkki Hölttä · Nature · 1981 · 143 citations

, , +15