Deficiency of WTAP in islet beta cells results in beta cell failure and diabetes in mice

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Dan Dominissini, Sharon Moshitch-Moshkovitz, Schraga Schwartz et al. · Nature · 2012 · 4.9K citations

Chromatin, Natural Sciences, Genetics +8

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

Jianzhao Liu, Yanan Yue, Dali Han et al. · Nature Chemical Biology · 2013 · 3.5K citations · Full text

Chromatin, Transcriptional Regulation, Medicine +8

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

Xiaoli Ping, Baofa Sun, Lu Wang et al. · Cell Research · 2014 · 2.4K citations · Full text

Engineering, Vivo Represent Mrnas, Genetics +20

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.

Hans E. Hohmeier, Hindrik Mulder, G Chen et al. · Diabetes · 2000 · 930 citations · Full text

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

Pedro L. Herrera · Development · 2000 · 661 citations

Genetics, Cell Specialization, Cellular Physiology +17