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Publication | Open Access

Impaired Adipocyte SLC7A10 Promotes Lipid Storage in Association With Insulin Resistance and Altered BCAA Metabolism

DOIFull Paper Access

11

Citations

59

References

2023

Year

Regine Å. Jersin, Divya Sri Priyanka Tallapragada, Linn Skartveit, Mona Synnøve Bjune, Maheswary Muniandy, Sindre Lee-Ødegård, Sini Heinonen, Marcus Alvarez, Kåre I. Birkeland, Christian A. Drevon,
The Journal of Clinical Endocrinology & Metabolism

Abstract

Reduced SLC7A10 activity strongly affects flux of BCAAs in adipocytes, which may fuel continued lipogenesis during insulin resistance, and be reflected in increased circulating levels of the valine-derived catabolite 3-HIB.

References

YearCitations

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