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Fragmentation of human cardiac troponin T after acute myocardial infarction

Ivan A. Katrukha, Natalia S. Riabkova, Alexander E Kogan, Alexandra V Vylegzhanina, Kadriya Sh. Mukharyamova, Agnessa P. Bogomolova, Artur I. Zabolotskii, Ekaterina V Koshkina, Anastasia V. Bereznikova, Alexey G Katrukha

Clinica Chimica Acta · 2023 · 24 citations · 23 references

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Abstract

cTnT progressively degrades after MI and appears in the blood as a mixture of 23 proteolytic fragments. The cTnT region approximately bordered by aar 69-158 is a promising target for antibodies used for measurement of total cTnT.

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