Exosomal miR-23b-3p from bone mesenchymal stem cells alleviates experimental autoimmune encephalomyelitis by inhibiting microglial pyroptosis

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

Yuan He, Melody Yue Zeng, Dahai Yang et al. · Nature · 2016 · 1.3K citations

Life Sciences, Immunology, Molecular Biology +17

Microglial control of astrocytes in response to microbial metabolites

Veit Rothhammer, Davis Borucki, Emily Tjon et al. · Nature · 2018 · 1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells

Makiko Ono, Nobuyoshi Kosaka, Naoomi Tominaga et al. · Science Signaling · 2014 · 703 citations

Medicine, Cell Biology, Oncology +17

Stem Cell-Derived Exosomes as Nanotherapeutics for Autoimmune and Neurodegenerative Disorders

Milad Riazifar, M. Rezaa Mohammadi, Egest J. Pone et al. · ACS Nano · 2019 · 555 citations

Life Sciences, Immunology, Neuroscience +17

Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis

Brienne McKenzie, Manmeet K. Mamik, Leina B. Saito et al. · Proceedings of the National Academy of Sciences · 2018 · 532 citations · Full text

Life Sciences, Neurology, Neuroscience +17