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Accumulation of NCOA1 dependent on HERC3 deficiency transactivates matrix metallopeptidases and promotes extracellular matrix degradation in intervertebral disc degeneration

Developmental BiologyHerc3 DeficiencyMetalloproteinNcoa1 DependentDegenerative DiseaseMatrix BiologyMedicineCell BiologyCell SignalingCellular PhysiologyIntervertebral Disc DegenerationExtracellular Matrix