The Risk for Cancer Or Dysplasia in Ulcerative Colitis Patients With Primary Sclerosing Cholangitis

Abstract

UC patients with PSC are at increased risk of developing CRC or dysplasia. Chronically active disease may be a risk factor, whereas folate could have a protective effect. CRCs associated with PSC are more likely to be proximal, to be diagnosed at a more advanced stage, and to be fatal.