Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever - Concepedia

Concepedia

Publication | Open Access

Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever

DOI Full Paper Access

33

Citations

33

References

2023

Year

Selina K. Jorch, Annika McNally, Philipp Berger, Jonas Wolf, Kim Kaiser, Andrian Chetrusca, Stefanie Robeck, Isabell Pastau, Olesja Fehler, Saskia-Larissa Jauch-Speer,

Journal of Allergy and Clinical Immunology

Abstract

This is the first proof that members of the S100 alarmin family are released in a pyrin/caspase-1/gasdermin D-dependent pathway and directly drive autoinflammation in vivo.

References

	Year	Citations

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