Global, regional, and national burden of multiple sclerosis from 1990 to 2019: Findings of global burden of disease study 2019

Abstract

The global cases of incidence, deaths, and DALYs of MS have all increased, whereas ASR has declined, with different trends in different regions. High SDI regions such as European countries have a substantial burden of MS. There are significant age effects for incidence, deaths, and DALYs of MS globally, and period effects and cohort effects for deaths and DALYs.