Chemical Communications · 2023 · 10 citations · 14 references
EngineeringBiotechnologyMolecular BiologyBiosensorsNanobiotechnologyNanomaterialsFluorescence ImagingFluorescence MicroscopyMolecular Probe DevelopmentNanomaterial-based BiosensorsOptical BiosensingOptical BiosensorsBiomolecular DetectionFluorescence Imaging ProbesFluorescent NanobiosensorsNanoparticle Imaging ProbesNanoparticle-based ProbesPolymer NanoparticlesSenescence-associated Beta-galactosidaseβ-Galactosidase Reporters
A near-infrared fluorescent nanoprobe based on semiconducting polymer nanoparticles (SPNs) for the detection of senescence-associated β-gal (SA-β-gal) is developed. Benefiting from the intrinsic lysosome-locating feature, this probe can be successfully used for the visualization of SA-β-gal in living cells.
14