Revista Brasileira de Terapia Intensiva · 2022 · 12 citations · 0 references
Veterinary MedicineInfectious DiseasesMicrobiologyAntimicrobial PharmacotherapyAntimicrobial ResistanceSepsisAntibiotic ResistanceAntimicrobial Resistance PreventionBacterial InfectionsHealthcare-associated Infection PreventionMultidrug ResistanceSeptic ShockHospital Antimicrobial Resistance SurveillanceIntensive Care Unit Antibiotic De-escalationIntensive Care Unit Antimicrobial StewardshipIntensive Care UseMultidrug Resistance DeterminantsMultidrug Resistance ManagementMultidrug-resistant Infection Treatment
OBJECTIVE: To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria. METHODS: We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform. RESULTS: The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database. CONCLUSION: The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials.