Infection Control and Hospital Epidemiology · 2023 · 15 citations · 7 references
MedicineInfectious DiseasesDiagnostic MicrobiologyMedical MicrobiologyMolecular DiagnosticsDiagnostic Test EvaluationGastrointestinal Pathogen DiagnosticsInfectious Disease Molecular TestingInfectious Disease ScreeningPathogen DetectionClostridial InfectionsClostridial Toxin DetectionClostridioides Difficile Infection TreatmentClostridioides Difficile TestingNucleic Acid AmplificationNucleic Acid Amplification DiagnosticsReal-world Performance EvaluationToxin Detection Assays
Abstract During the 4 years after implementation of the 2-step Clostridioides difficile infection (CDI) testing algorithm, 70% to 78% of patients with suspected CDI and a positive nucleic acid amplification test but a negative toxin test (NAAT+/TOX−) received CDI treatment. Overall, 73% of NAAT+/TOX− patients were classified as having probable or possible CDI.
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L. Clifford McDonald, Dale N. Gerding, Stuart Johnson et al. · Clinical Infectious Diseases · 2017 · 2.7K citations · Full text
Ryan Miller, Jose A. Morillas, Kyle D. Brizendine et al. · Journal of Clinical Microbiology · 2020 · 33 citations · Full text