Transcriptional analysis of nasal polyps fibroblasts reveals a new source of pro-inflammatory signaling in CRSwNP - Concepedia

Concepedia

Publication | Open Access

Transcriptional analysis of nasal polyps fibroblasts reveals a new source of pro-inflammatory signaling in CRSwNP

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References

2023

Year

Cristina Porras‐González, José María Palacios-García, Serafín Sánchez‐Gómez, Juan M. Solano, Gonzalo Álba, Víctor Sánchez‐Margalet, Óscar Palomares, A del Cuvillo, Juan Antonio Cordero Varela, Ramón Moreno‐Luna,

Rhinology Journal

Abstract

Our work reveals a potential new source of inflammatory signaling in CRSwNP. Furthermore, our results suggest that deregulated inflammatory signaling in tissue-resident fibroblasts could support a Type-2 inflammatory response. Further investigations will be necessary to demonstrate the functionality of these novel results.