Concepedia

5-HT attenuates chronic stress-induced cognitive impairment in mice through intestinal flora disruption

Junxing Ma, Ran Wang, Yaoxing Chen, Zixu Wang, Yulan Dong

Journal of Neuroinflammation · 2023 · 111 citations · 58 references

DOIFull text

Open access

Abstract

These results strongly suggest that L. lactis E001-B-8 but not FLX can alleviate rodent depressive and anxiety-like behaviours in response to CUMS, which is associated with the improvement of 5-HT metabolism and modulation of the gut microbiome composition.

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