A decrease in <scp>NR2B</scp> expression mediated by <scp>DNA</scp> hypermethylation induces perioperative neurocognitive disorder in aged mice - Concepedia

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A decrease in <scp>NR2B</scp> expression mediated by <scp>DNA</scp> hypermethylation induces perioperative neurocognitive disorder in aged mice

DOI Full Paper Access

27

Citations

42

References

2023

Year

Feifei Xu, Peilin Cong, Bing-Qian Zhang, Hailong Dong, Wenqiang Zuo, Tingmei Wu, Tian Li, Lize Xiong

CNS Neuroscience & Therapeutics

Abstract

Laparotomy cause hippocampus-dependent cognitive decline by hypermethylating the NR2B gene, allowing us to understand the pathogenesis of PND in an epigenetic landscape.

References

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