Hepatic pIgR-mediated secretion of IgA limits bacterial translocation and prevents ethanol-induced liver disease in mice - Concepedia

Concepedia

Publication | Open Access

Hepatic pIgR-mediated secretion of IgA limits bacterial translocation and prevents ethanol-induced liver disease in mice

DOI Full Paper Access

26

Citations

34

References

2023

Year

Tim Hendrikx, Sonja Lang, Dragana Rajcic, Yanhan Wang, Sara McArdle, Kenneth Kim, Zbigniew Mikulski, Bernd Schnabl

Abstract

Our results highlight that dysfunctional hepatic pIgR enhances alcohol-associated liver disease due to impaired antimicrobial defence by IgA in the gut.

References

	Year	Citations

Page 1