Contralateral Breast Cancer Risk Among Carriers of Germline Pathogenic Variants in<i>ATM</i>,<i>BRCA1</i>,<i>BRCA2</i>,<i>CHEK2</i>, and<i>PALB2</i>

Abstract

Women diagnosed with breast cancer and known to carry germline PVs in <i>BRCA1</i>, <i>BRCA2</i>, <i>CHEK2</i>, or <i>PALB2</i> are at substantially increased risk of CBC and may benefit from enhanced surveillance and risk reduction strategies.