Inorganic Chemistry Frontiers · 2022 · 26 citations · 35 references
MedicineMedicinal ChemistryPharmacologyCancer PharmacologyChemotherapyDrug DiscoveryAntineoplastic Drug InteractionsCoordination ChemistryLigand BindingTargeting LigandsOrganometallic Anticancer AgentsPlatinum CompoundsPlatinum-based AgentsTumor Targeting Ligands
Two Palladium complexes are presented as a promising alternative to platinum drugs disadvantages, controlling the speciation and limiting toxicity. Their interaction vs. biological targets and their efficiency are demonstrated, being more specific than the benchmark cisplatin drug.
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