Green synthesis of silver nanoparticles, graphene, and silver-graphene nanocomposite using <i>Melissa officinalis</i> ethanolic extract: Anticancer effect on MCF-7 cell line.

Abstract

Treatment of MCF-7 cells with silver or graphene nanoparticles and combination treatment with these two substances against cisplatin have sound effects, and by affecting oxidative stress factors, such as increased ROS and subsequent increase in lipid membrane damage, inhibit cell growth and proliferation. According to the mathematical model, silver graphene nanocomposite> silver nanoparticles> graphene has the best effect in inhibiting the growth of cancer cells, respectively.