Concepedia

Multiplex immunofluorescence and single‐cell transcriptomic profiling reveal the spatial cell interaction networks in the non‐small cell lung cancer microenvironment

Haoxin Peng, Xiangrong Wu, Shaopeng Liu, Miao He, Chao Xie, Ran Zhong, Jun Liu, Chenshuo Tang, Caichen Li, Shan Xiong,

Clinical and Translational Medicine · 2023 · 77 citations · 53 references

DOIFull text

Open access

Abstract

We developed a framework to analyse the cell interaction networks in tumour microenvironment, revealing the spatial architecture and intricate interplays between immune and tumour cells.

References

53

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Hyuna Sung, Jacques Ferlay, Rebecca L. Siegel et al. · CA A Cancer Journal for Clinicians · 2021 · 109.5K citations · Full text

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 54.5K citations · Full text

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limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E. Ritchie, Belinda Phipson, Di Wu et al. · Nucleic Acids Research · 2015 · 40.9K citations · Full text

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World Medical Association Declaration of Helsinki

JAMA · 2013 · 27.3K citations

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clusterProfiler 4.0: A universal enrichment tool for interpreting omics data

Tianzhi Wu, Erqiang Hu, Shuangbin Xu et al. · The Innovation · 2021 · 12.1K citations · Full text