Transition Metal Catalyzed Asymmetric Hydroboration of Internal Alkenes

Abstract

Transition metal catalyzed asymmetric hydroboration of alkenes is one of the most powerful methods to prepare chiral organoboronates, which has attracted extensive attention of chemists due to its simple raw materials, high atomic economy, diverse structure of borated products, etc. The transition metal catalyzed enantioselective hydroboration of internal alkenes including strained internal alkene, -substituted styrenes and internal alkenes bearing a coordinating group is summarized.