Catalyst-free aerobic radical cascade reactions of <i>o</i>-vinylphenylisocyanides with thiols to access 2-thio-substituted quinolines

Abstract

We herein report an efficient and green aerobic radical cascade reaction of o -vinylphenylisocyanides with thiols to access a broad range of 2-thio-substituted quinolines without the need for additional catalysts or oxidants.