Concepedia

Publication | Open Access

Targeting ULK1 Decreases IFNγ-Mediated Resistance to Immune Checkpoint Inhibitors

DOIFull Paper Access

14

Citations

39

References

2022

Year

Sarah E. Fenton, Liliana Ilut, Mariafausta Fischietti, Chunni Ji, Chidera V. Oku, Curt M. Horvath, I. Caroline Le Poole, Marcus Bosenberg, Elizabeth T. Bartom, Masha Kocherginsky,
Molecular Cancer Research

Abstract

This study identifies ULK1, activated downstream of IFNγ signaling, as a druggable target to overcome resistance mechanisms to ICI therapy in metastatic melanoma.

References

YearCitations

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