Multi-omics pan-cancer study of cuproptosis core gene FDX1 and its role in kidney renal clear cell carcinoma

Abstract

Our analysis showed that the central regulatory gene of cuproptosis, <i>FDX1</i>, has differential expression and modification levels in various tumors, which is associated with cellular function, immune modulation, and disease prognosis. Thus, <i>FDX1</i>-dependent cuproptosis may serve as a brand-new target in future therapeutic approaches against tumors.