Associations of low sex hormone‐binding globulin and androgen excess in early pregnancy with fasting and post‐prandial hyperglycaemia, gestational diabetes, and its severity

Abstract

Lower SHBG levels were associated especially with early-onset GDM, higher fasting glucose and insulin treatment, whereas androgen excess was associated with higher post-prandial glucose values. Thus, a low SHBG level may reflect the degree of existing insulin resistance, while androgen excess might impair post-prandial insulin secretion.