<scp>NLRP3</scp> Attenuates Intraocular Inflammation by Inhibiting <scp>AIM2‐Mediated</scp> Pyroptosis Through the Phosphorylated <scp>Salt‐Inducible</scp> Kinase 1/Sterol Regulatory Element Binding Transcription Factor 1 Pathway - Concepedia

Concepedia

Publication | Closed Access

<scp>NLRP3</scp> Attenuates Intraocular Inflammation by Inhibiting <scp>AIM2‐Mediated</scp> Pyroptosis Through the Phosphorylated <scp>Salt‐Inducible</scp> Kinase 1/Sterol Regulatory Element Binding Transcription Factor 1 Pathway

33

Citations

39

References

2022

Year

Jiayu Meng, Na Li, Xianyang Liu, Shengjun Qiao, Qian Zhou, Jun Tan, Ting Zhang, Zhifang Dong, Xiaopeng Qi, Aize Kijlstra,

Arthritis & Rheumatology

Abstract

Our data demonstrate that NLRP3 inhibits AIM2 inflammasome-mediated EAU by regulating the p-SIK1/SREBF1 pathway, highlighting the therapeutic potential of targeting Nlrp3.

References

	Year	Citations

Page 1