Iridium-catalyzed regioselective B(3,6)-dialkenylation or B(4)-alkenylation of <i>o</i>-carboranes <i>via</i> B–H activation and 1,2-carbon migration of alkynes

Abstract

An efficient Ir-catalyzed cage boron alkenylation of 1-(2'-picolyl)-<i>o</i>-carboranes with diarylacetylenes has been developed, leading to a wide variety of B-H geminal addition products <i>via</i> 1,2-carbon migration of alkynes. The steric effect of cage carbon substituents has a great impact on the regioselectivity of such alkenylation reactions.