Longitudinal Assessment of Creatine Kinase, Creatine/Creatinine_ratio, and Myostatin as Monitoring Biomarkers in Becker Muscular Dystrophy

Abstract

Both Cr/Crn and myostatin could potentially serve as monitoring biomarkers in BMD, as higher Cr/Crn and lower myostatin were associated with lower motor performance and predictive of concurrent functional performance when combined with age. Future studies are needed to more precisely determine the context of use of these biomarkers.