Concepedia

Publication | Open Access

Lumican Accumulates with Fibrillar Collagen in Fibrosis in Hypertrophic Cardiomyopathy

DOIFull Paper Access

30

Citations

35

References

2022

Year

Chloe Rixon, Kristine Andreassen, Xin Shen, Pugazendhi M Erusappan, Vibeke Marie Almaas, Sheryl Palmero, Christen P. Dahl, Thor Ueland, Ivar Sjaastad, William E. Louch,
ESC Heart Failure

Abstract

The ECM proteoglycan lumican is increased in HCM and co-localizes with fibrillar collagen throughout areas of fibrosis in HCM. Our data suggest that lumican may promote formation of thicker collagen fibres in HCM.

References

YearCitations

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