Reduced cerebral cortex thickness is related to overexpression of exosomal miR-146a-5p in medication-free patients with major depressive disorder

Abstract

The findings of this study reveal a relationship between miR-146a-5p overexpression and cortical atrophy and thus may help specify the <i>in vivo</i> mediating effect of miR-146a-5p dysregulation on brain structural abnormalities in patients with MDD.