Identifying Good Candidates for Active Surveillance of Ductal Carcinoma <i>In Situ</i> : Insights from a Large Neoadjuvant Endocrine Therapy Cohort

Abstract

A retrospective analysis of 71 patients with DCIS who did not undergo upfront surgery demonstrated that breast MRI features after short-term exposure to endocrine therapy identify those at high (68.2%), intermediate (20.0%), and low risk (8.7%) of IDC. With 7.4 years mean follow-up, 52.1% of patients remain on active surveillance. A period of active surveillance offers the opportunity to risk-stratify DCIS lesions and guide decisions for operative management.