Gene Expression and Autoantibody Analysis Revealing Distinct <scp>Ancestry‐Specific</scp> Profiles Associated With Response to Rituximab in Refractory Systemic Lupus Erythematosus

Abstract

Ancestry appears central to the immunologic and clinical heterogeneity in SLE. These results suggest that ancestry, disease activity, and transcriptional signatures could each assist in predicting the effectiveness of B cell depletion therapies.