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The E3 ubiquitin ligase CHIP protects against sepsis-induced myocardial dysfunction by inhibiting NF-κB-mediated inflammation via promoting ubiquitination and degradation of karyopherin-α 2

InflammationHeart FailureDisease PathophysiologyImmune RegulationImmunologyChronic InflammationSepsis-induced Myocardial DysfunctionCardiologyInnate ImmunityMedicineCell BiologyCell SignalingNf-κb-mediated InflammationKaryopherin-α 2Cardiac Pathology