1e:T46e,Several mechanisms in industrial use have significant applications in thermal transportation. The inclusion of hybrid nanoparticles in different mixtures has been studied extensively by researchers due to their wide applications. This report discusses the flow of Powell–Eyring fluid mixed with hybrid nanoparticles over a melting parabolic stretched surface. Flow rheology expressions have been derived under boundary layer theory. Afterwards, similarity transformation has been applied to convert PDEs into associated ODEs. These transformed ODEs have been solved the using finite element procedure (FEP) in the symbolic computational package MAPLE 18.0. The applicability and effectiveness of FEM are presented by addressing grid independent analysis. The reliability of FEM is presented by computing the surface drag force and heat transportation coefficient. The used methodology is highly effective and it can be easily implemented in MAPLE 18.0 for other highly nonlinear problems. It is observed that the thermal profile varies directly with the magnetic parameter, and the opposite trend is recorded for the Prandtl number.1f:T4b2,The design of bioactive supramolecular chirality is always hampered by the lack of feasible schemes to assigned specific biological activities. Herein, we developed a "mirror-image peptide grafting" method to graft the epitopes of bioactive d-peptide onto the miniprotein template to construct a self-assembled supraparticle. Grafting ^DPMI^β, a 12-mer d-enantiomeric peptide functioned as the p53 agonist, onto Apamin, we successfully constructed a self-assembled d-enantiomeric miniprotein supermolecule nanoparticle, termed ^DMSN. This chiral supraparticle possesses a favorable pharmaceutical profile including the passive tumor targeting, cell membrane penetration, intracellular reductive responsiveness, and endosome escaping. ^DMSN showed in vitro and in vivo p53-dependent antiproliferative activity and augmented antitumor immunity elicited by anti-PD1 therapy. This enabling strategy will allow us to fabricate a class of peptide/protein-derived supramolecular chirality with predictable biological activities and will likely have a broad impact on the chiral nanotechnology at the service of prevention and treatment of human diseases.20:T40e,The current focus of development in industrial Computational Fluid Dynamics (CFD) is integration of CFD into Computer-Aided product development, geometrical optimisation, robust design and similar. On the other hand, in CFD research aims to extend the boundaries of practical engineering use in "non-traditional" areas. Requirements of computational flexibility and code integration are contradictory: a change of coding paradigm, with object orientation, library components, equation mimicking is proposed as a way forward. This paper describes OpenFOAM, a C++ object oriented library for Computational Continuum Mechanics (CCM) developed by the author. Efficient and flexible implementation of complex physical models is achieved by mimicking the form of partial differential equation in software, with code functionality provided in library form. Open Source deployment and development model allows the user to achieve desired versatility in physical modeling without the sacrifice of complex geometry support and execution efficiency.

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