Oltipraz, the activator of nuclear factor erythroid 2-related factor 2 (Nrf2), protects against the formation of BAPN-induced aneurysms and dissection of the thoracic aorta in mice by inhibiting activation of the ROS-mediated NLRP3 inflammasome

Publication | Closed Access

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2022

Year

Dashuai Wang, Jia Wu, Sheng Le, Hongfei Wang, Jingjing Luo, Rui Li, Xing Chen, Yu Song, Ping Ye, Xinling Du,

European Journal of Pharmacology

InflammationAnti-inflammatorySignal TransductionMedicineBapn-induced AneurysmsImmunologyEndothelial DysfunctionThoracic AortaVascular BiologyRos-mediated Nlrp3 InflammasomeReactive Oxygen SpeciePharmacologyCell BiologyCell SignalingOxidative Stress