Comprehensive investigation on the metabolism of emodin both in vivo and in vitro

The profiling and identification of the absorbed constituents and metabolites of Paeoniae Radix Rubra decoction in rat plasma and urine by the HPLC–DAD–ESI-IT-TOF-MSn technique: A novel strategy for the systematic screening and identification of absorbed constituents and metabolites from traditional Chinese medicines

Jing Liang, Feng Xu, Yazhou Zhang et al. · Journal of Pharmaceutical and Biomedical Analysis · 2013 · 144 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +13

Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin

Wei Liu, Qian Feng, Li Ye et al. · Toxicology and Applied Pharmacology · 2012 · 99 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

The effect of emodin on cytotoxicity, apoptosis and antioxidant capacity in the hepatic cells of grass carp (Ctenopharyngodon idellus)

Yanting Cui, Bo Liu, Jun Xie et al. · Fish & Shellfish Immunology · 2014 · 89 citations

Life Sciences, Biochemistry, Toxicology +17

Differences in pharmacokinetics and ex vivo antioxidant activity following intravenous and oral administrations of emodin to rats**Chi-Sheng Shia and Yu-Chi Hou contributed equally to this work.

Chi‐Sheng Shia, Yu‐Chi Hou, Shang-Yuan Tsai et al. · Journal of Pharmaceutical Sciences · 2009 · 89 citations

Life Sciences, Pharmacokinetics, Pharmacology +14

Antibiotics may increase triazine herbicide exposure risk via disturbing gut microbiota

Jing Zhan, Yiran Liang, Donghui Liu et al. · Microbiome · 2018 · 66 citations · Full text

Veterinary Medicine, Microbiology, Toxicology +17