High frame rate deformation analysis of knee cartilage by spiral <scp>dualMRI</scp> and relaxation mapping

Abstract

Our results indicate that spiral scanning with displacement encoding can quantitatively differentiate the damaged from intact joint using the strain and creep response. The viscoelastic response identified with this methodology could serve as biomarkers to detect defects in joints in vivo and facilitate the early diagnosis of joint diseases such as osteoarthritis.