Concepedia

1-Methyl-3-((4-(quinolin-4-yloxy)phenyl)amino)-1H-pyrazole-4-carboxamide derivatives as new rearranged during Transfection (RET) kinase inhibitors capable of suppressing resistant mutants in solvent-front regions

Yunong Zhang, Shinpan Chan, Rui He, Yiling Liu, Xiaojuan Song, Zhengchao Tu, Xiaomei Ren, Yang Zhou, Zhang Zhang, Zhen Wang,

European Journal of Medicinal Chemistry · 2022 · 13 citations · 50 references

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References

50

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Marcia S. Brose, Christopher M. Nutting, Barbara Jarząb et al. · The Lancet · 2014 · 1.6K citations · Full text

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Vandetanib in Patients With Locally Advanced or Metastatic Medullary Thyroid Cancer: A Randomized, Double-Blind Phase III Trial

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Activation of a novel human transforming gene, ret, by DNA rearrangement

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