Concepedia

YME1L overexpression exerts pro-tumorigenic activity in glioma by promoting Gαi1 expression and Akt activation

Fang Liu, Gang Chen, Li-Na Zhou, Yin Wang, Zhi-qing Zhang, Xihu Qin, Cong Cao

Protein & Cell · 2022 · 24 citations · 15 references

DOIFull text

Open access

Concepts

References

15

The <i>i</i>-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

Ruchika Anand, Timothy Wai, Michael J. Baker et al. · The Journal of Cell Biology · 2014 · 779 citations

, , +17

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

Timothy Wai, Jaime García‐Prieto, Michael J. Baker et al. · Science · 2015 · 543 citations

, , +17

Lipid signalling drives proteolytic rewiring of mitochondria by YME1L

Thomas MacVicar, Yohsuke Ohba, Hendrik Nolte et al. · Nature · 2019 · 185 citations

, , +12

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation

Lukáš Stibůrek, Jana Cesnekova, Olga Kostková et al. · Molecular Biology of the Cell · 2012 · 178 citations · Full text

, , +17

Gα <sub>i1</sub> and Gα <sub>i3</sub> Are Required for Epidermal Growth Factor–Mediated Activation of the Akt-mTORC1 Pathway

Cong Cao, Xuesong Huang, Yuyuan Han et al. · Science Signaling · 2009 · 136 citations

, , +16