Overcoming high level adenosine-mediated immunosuppression by DZD2269, a potent and selective A2aR antagonist

References

Page 1

	Year	Citations
Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer Lawrence Fong, Andrew Hotson, John D. Powderly, Cancer Discovery	2019	321
Adenosine Receptor 2A Blockade Increases the Efficacy of Anti–PD-1 through Enhanced Antitumor T-cell Responses Paul A. Beavis, Nicole Milenkovski, Melissa A. Henderson, Cancer Immunology Research ImmunologyImmune RegulationImmunoeditingCd4 T Cell ResponsesImmunotherapeutics	2015	314
Myeloid Expression of Adenosine A2A Receptor Suppresses T and NK Cell Responses in the Solid Tumor Microenvironment Caglar Cekic, Yuan‐Ji Day, Duygu Sağ, Cancer Research	2014	282
A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes Alberto L. Horenstein, Antonella Chillemi, Gianluca Zaccarello, OncoImmunology	2013	265
Chemotherapy induces ATP release from tumor cells Isabelle Martins, Antoine Tesnière, Oliver Kepp, Cell Cycle	2009	264
Purinergic signaling, DAMPs, and inflammation Francesco Di Virgilio, Alba Clara Sarti, Robson Coutinho‐Silva American Journal of Physiology-Cell Physiology Cell DeathCellular PhysiologyPurinergic SignalingInflammationExtracellular Atp	2020	224
A2AR Antagonism with CPI-444 Induces Antitumor Responses and Augments Efficacy to Anti–PD-(L)1 and Anti–CTLA-4 in Preclinical Models Stephen B. Willingham, Po Y. Ho, Andrew Hotson, Cancer Immunology Research	2018	209
The Dendritic Cell Response to Classic, Emerging, and Homeostatic Danger Signals. Implications for Autoimmunity Paul M. Gallo, Stefania Gallucci Frontiers in Immunology Dendritic Cell ResponseImmune ActivationImmunologyImmune RegulationImmunologic Mechanism	2013	186
Blockade of adenosine A2A receptor enhances CD8+ T cells response and decreases regulatory T cells in head and neck squamous cell carcinoma Si‐Rui Ma, Wei‐Wei Deng, Jianfeng Liu, Molecular Cancer	2017	176
LPS-induced cytokine production in human dendritic cells is regulated by sialidase activity Nicholas M. Stamatos, Ivan Carubelli, Diantha van de Vlekkert, Journal of Leukocyte Biology ImmunologyGlycobiologyInnate ImmunityImmune SystemImmunotherapy	2010	98

Page 1